This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
HCN1 Antibody LS-C15642
catalog :
LS-C15642
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
16383
AntibodyName :
LS-C15642
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
HCN1 Antibody LS-C15642
Specificity :
The pore region of HCN1 (HCNP15-P) is very conserved among various HCNs. HCN1: mouse, rat, human, rabbit=100%; HCN2: mouse, rat, human (86%); HCN3: mouse (95%), rat (90%); HCN4: rat, human (95%). The HCNP15-P sequence is also conserved in insect (Helothis virescens, 78%), Drosophila (78%) and Sea urchin (S. purpuratus, 69%) HCNs. Therefore, antibodies to HCNP15-P should react with most HCNs and related sequences. Antibody reactivity in various species is not known. The HCNP15-P control peptide, because of its low MW (<3kD), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity. This antibody may be useful in studying various HCNs and to examine the possibility of immunoblocking the pore region and impact on the functionality of HCNs proteins.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.1% BSA
ImmunogenDesc :
A 23 aa peptide sequence corresponding to the pore region of human HCN1 corresponding to amino acids 346-368.
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
IsotypeName :
IgG
Gene :
HCN1
StandardGeneSymbol :
HCN1
gene family :
Ion Channel
Subfamily :
Potassium channel - cyclic nucleotide gated
Reactivity :
Rabbit, Mouse, Rat, Human
Usage :
ELISA (1:10000 - 1:100000), WB (1 - 10 µg/ml)
ShortWebDescription :
HCN1 antibody LS-C15642 is an unconjugated rabbit polyclonal antibody to HCN1 from human. It is reactive with human, mouse, rat and other species. Validated for ELISA and WB.
UsageText :
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 ug/ml for affinity pure using ECL. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
Synonyms :
HCN1, BCNG1, BCNG-1, HAC2, HAC-2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.