product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IDO1 / IDO Antibody (clone 10.1) LS-C153780
catalog :
LS-C153780
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10.1
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:100; fig 2
  • immunohistochemistry; human
Gulati N, Suárez Fariñas M, Correa Da Rosa J, Krueger J. Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions. F1000Res. 2015;4:149 pubmed publisher
Ohmatsu H, Humme D, Gonzalez J, Gulati N, Möbs M, Sterry W, et al. IL-32 induces indoleamine 2,3-dioxygenase+CD1c+ dendritic cells and indoleamine 2,3-dioxygenase+CD163+ macrophages: Relevance to mycosis fungoides progression. Oncoimmunology. 2017;6:e1181237 pubmed publisher
Schafer C, Wang Y, Hough K, Sawant A, Grant S, Thannickal V, et al. Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment. Oncotarget. 2016;7:75407-75424 pubmed publisher
Batista C, Juhasz C, Muzik O, Kupsky W, Barger G, Chugani H, et al. Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors. Mol Imaging Biol. 2009;11:460-6 pubmed publisher
Zhu L, Ji F, Wang Y, Zhang Y, Liu Q, Zhang J, et al. Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J Immunol. 2006;177:8226-33 pubmed
product information
AntibodyID :
160455
AntibodyName :
LS-C153780
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IDO1 / IDO Antibody (clone 10.1) LS-C153780
Specificity :
This antibody is specific for human and mouse IDO1 protein. A BLAST analysis was used to suggest cross-reactivity with IDO1 from human and mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with IDO1 from other sources has not been determined.
ClonalityDesc :
Monoclonal
CloneName :
10.1
AntibodyModification :
Unconjugated
PresentationDesc :
0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
PurificationDesc :
Protein G affinity chromatography
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG3
Gene :
IDO1 / IDO
StandardGeneSymbol :
IDO1
Reactivity :
Mouse, Human
Usage :
ELISA (1:5000 - 1:50000), IF (1:50 - 1:100), IHC (1:100 - 1:500), IP, WB (1:500 - 1:1500)
ShortWebDescription :
IDO antibody LS-C153780 is an unconjugated mouse monoclonal antibody to IDO (IDO1) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC, IP and WB. Cited in 5 publications.
UsageText :
Anti-IDO1 antibody has been tested for use in ELISA, Western Blot, IP and IHC. Specific conditions for reactivity should be optimized by the end user.
Synonyms :
IDO1, IDO, Indole 2,3-dioxygenase, Indolamine 2,3 dioxygenase, IDO-1, INDO, Indoleamine 2,3-dioxygenase, Indoleamine 2,3-dioxygenase 1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.