product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IPAF / NLRC4 Antibody LS-C148271
catalog :
LS-C148271
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Guo Y, Li L, Xu T, Guo X, Wang C, Li Y, et al. HUWE1 mediates inflammasome activation and promotes host defense against bacterial infection. J Clin Invest. 2020;130:6301-6316 pubmed publisher
Ma J, Gulbins E, Edwards M, Caldwell C, Fraunholz M, Becker K. Staphylococcus aureus ?-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides. Cell Physiol Biochem. 2017;43:2170-2184 pubmed publisher
product information
AntibodyID :
153476
AntibodyName :
LS-C148271
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IPAF / NLRC4 Antibody LS-C148271
Specificity :
Ipaf.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Antiserum, 0.05% sodium azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to amino acis 637-654 (EEAPETYIPSRAVSLFFN) of Ipaf/Clan/CARD12, GenBank no. gi 40788015 ref NP_067032.3 . This peptide immunogen sequence is 100% conserved in mouse. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Hamster (89%); Mouse, Rat, Bat, Horse (83%).
PurificationDesc :
Antiserum
RecommendedStorageDesc :
Store at -20°C. Avoid freeze/thaw cycles.
Gene :
IPAF / NLRC4
StandardGeneSymbol :
NLRC4
gene family :
Apoptosis
Reactivity :
Mouse, Human
Usage :
IHC, IHC-Fr, IHC-P (1:1000 - 1:5000), IP (1:50 - 1:200), WB (1:1000 - 1:2000)
ShortWebDescription :
NLRC4 antibody LS-C148271 is an unconjugated rabbit polyclonal antibody to NLRC4 (IPAF) from human. It is reactive with human and mouse. Validated for IHC, IP and WB. Cited in 2 publications.
Synonyms :
NLRC4, CARD12, CLANA, CLANB, CLANC, CLAND, CLAN, CLR2.1, Clan protein, CLAN1, Ice protease-activating factor, NOD-like receptor C4, ICE-protease activating factor, IPAF
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.