This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TLR4 Antibody (clone HTA125, PE) LS-C148165
catalog :
LS-C148165
clonality :
monoclonal
host :
mouse
conjugate :
PE
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
153370
AntibodyName :
LS-C148165
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
TLR4 Antibody (clone HTA125, PE) LS-C148165
Specificity :
This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This has been demonstrated to block activation of monocytes with LPS.
ClonalityDesc :
Monoclonal
CloneName :
HTA125
AntibodyModification :
PE
PresentationDesc :
PBS, 0.05% Sodium Azide, 0.05% BSA
ImmunogenType :
Cells
ImmunogenDesc :
This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for up to 6 months at 4°C. Protect from light.
IsotypeName :
IgG2a,k
Gene :
TLR4
StandardGeneSymbol :
TLR4
gene family :
Toll-like Receptor
Reactivity :
Dog, Human
Usage :
Flo (1 - 2 µg/10E6 cells)
ShortWebDescription :
TLR4 antibody LS-C148165 is a PE-conjugated mouse monoclonal antibody to TLR4 from human. It is reactive with human and dog. Validated for Flow.
UsageText :
Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.