product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
CFTR Antibody (aa103-117) LS-C14758
catalog :
LS-C14758
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Gonzalez G, Vituret C, Di Pietro A, Chanson M, Boulanger P, Hong S. Microparticle-mediated transfer of the viral receptors CAR and CD46, and the CFTR channel in a CHO cell model confers new functions to target cells. PLoS ONE. 2012;7:e52326 pubmed publisher
product information
AntibodyID :
15499
AntibodyName :
LS-C14758
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CFTR Antibody (aa103-117) LS-C14758
Specificity :
Recognizes human CTFR. Also detects one or more immunologically related proteins in murine cell line Heb7a that does not contain CFTR mRNA. This antibody can also be used to inhibit the epithelial uptake of S. typhi in some mouse cell lines. Species cross-reactivity: Mouse.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa103-117
PresentationDesc :
0.05% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide: G(103)RIIASYDPDNKEER(117). Immunizing peptide corresponds to Synthetic peptide from residues 103-117 found in the first extracellular loop of human and rabbit CFTR. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Ferret, Guinea pig (100%); Galago, Marmoset, Rat, Sheep, Hamster, Elephant, Panda, Bovine, Cat, Bat, Dog, Rabbit, Pig, Armadillo (93%); Mouse, Horse, Opossum, Chicken, Platypus (86%).
PurificationDesc :
Ascites
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgM
Gene :
CFTR
StandardGeneSymbol :
CFTR
gene family :
Transporter
Subfamily :
ATP-binding cassette - ABCC/MRP
Reactivity :
Guinea pig, Human
Usage :
IF (1:500), IP, WB (1:500)
ShortWebDescription :
CFTR antibody LS-C14758 is an unconjugated mouse monoclonal antibody to CFTR (aa103-117) from human. It is reactive with human and guinea pig. Validated for IF, IP and WB. Cited in 1 publication.
UsageText :
Suitable for use in Immunofluorescence, Immunoprecipitation and Western Blot. Immunofluorescence: 1:500; Immunofluorescence staining of CFTR in mouse epithelial cells results in cell surface staining, consistent with localization at the plasma membrane. Western Blot: 1:500; Detects a single ~170kD protein representing CFTR in T84 whole cell extract.
Synonyms :
CFTR, ABC35, ABCC7, CF, DJ760C5.1, MRP7, CFTR/MRP, TNR-CFTR
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.