product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-ABCG2
catalog :
LS-C134869
quantity :
price :
clonality :
monoclonal
host :
rat
reactivity :
human
application :
western blot, flow cytometry, immunohistochemistry, immunohistochemistry - frozen section
product information
?AntibodyID :
138550
AntibodyName :
LS-C134869
TargetSpecies :
human
Host Species :
rat
Product Name :
Anti-ABCG2
Specificity :
The BXP-53 Mab was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the mouse bcrp protein corresponding to amino acids 221-394. BXP-53 reacts with an internal epitope of bcrp, a 70 kD transmembrane half-transporter which is involved in Multidrug resistance. BXP-53 also reacts with the human BCRP molecule.
ClonalityDesc :
monoclonal
CloneName :
BXP-53
AntibodyModification :
Unconjugated
PresentationDesc :
Tissue culture supernatant (serum-free), 0.7% BSA, 0.1% sodium azide
PurificationDesc :
Tissue Culture Supernatant
RecommendedStorageDesc :
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
IsotypeName :
IgG2a
gene :
ABCG2
StandardGeneSymbol :
ABCG2
gene family :
Transporter
Subfamily :
ATP-binding cassette - ABCG/WHITE
reactivity :
human
Usage :
Flo, IHC-Fr, WB
UsageText :
Immunocytochemistry: use 1:20-50 dilution. on acetone fixed cytospin preparations. For immunohistochemistry: BXP-53 (use 1:20) on acetone fixed frozen sections can be followed by incubation with biotin-labeled rabbit anti-rat IgG (1:100, Dako) and HRP-labeled streptavidin (1:500, Dako). Western blotting: use 1:20-50 dilution and HRP-anti-rat-IgG. Flow cytometry: optimal conditions still to be defined.
Synonyms :
ABCG2, ABC transporter, ABCP, BCRP1, CD338, CD338 antigen, ABC15, GOUT1, MRX, MXR, MXR1, UAQTL1, Placenta specific MDR protein, BCRP, BMDP, CDw338, EST157481
SwissProtProtoID :
Q9UNQ0
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
Headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.