product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
GREM1 / Gremlin-1 Antibody (clone 4C2) LS-C125371
catalog :
LS-C125371
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C2
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry knockout validation
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:250; loading ...; fig 4c
Chang S, Mori D, Kobayashi H, Mori Y, Nakamoto H, Okada K, et al. Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway. Nat Commun. 2019;10:1442 pubmed publisher
product information
AntibodyID :
128991
AntibodyName :
LS-C125371
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
GREM1 / Gremlin-1 Antibody (clone 4C2) LS-C125371
Specificity :
Recognizes human Gremlin 1. Cross reactivity with mouse.
ClonalityDesc :
Monoclonal
CloneName :
4C2
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized PBS, pH 7.4
ImmunogenDesc :
Partial recombinant human Gremlin-1 (75-185) with a GST tag.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C lyophilized. Once reconstituted: Store at -20°C. Aliquot to avoid freeze-thaw cycles.
ResuspensionLiquidDesc :
Reconstitute with 100ul sterile ddH2O
IsotypeName :
IgG
Gene :
GREM1 / Gremlin-1
StandardGeneSymbol :
GREM1
Reactivity :
Mouse, Human
Usage :
ELISA, WB
ShortWebDescription :
Gremlin-1 antibody LS-C125371 is an unconjugated mouse monoclonal antibody to Gremlin-1 (GREM1) from human. It is reactive with human and mouse. Validated for ELISA and WB. Cited in 1 publication.
UsageText :
Suitable for use in ELISA and Western Blot.
Synonyms :
GREM1, CKTSF1B1, DAN domain family member 2, DAND2, DRM, GREMLIN, Gremlin 1-like protein, Increased in high glucose-2, Gremlin-1, PIG2, Proliferation-inducing gene 2, Gremlin 1, IHG-2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.