This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CASP3 / Caspase 3 Antibody (N-Terminus) LS-C12494
catalog :
LS-C12494
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
13235
AntibodyName :
LS-C12494
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
CASP3 / Caspase 3 Antibody (N-Terminus) LS-C12494
Specificity :
Recognizes human caspase-3. In apoptotic cells, this antibody also detects 20kD and 18kD proteins which correspond to the processed forms of caspase-3. Following the induction of apoptosis and the appearance of these smaller bands, a concurrent reduction in the amount of the procaspase enzyme is noted on immunoblot analysis. A weak ~30kD band may be detected in some samples. This band is not caspase-3 as it is detected in MCF7 cell lysates which lack the caspase-3 protein. Species cross-reactivity: mouse, rat, bovine, canine, chicken, guinea pig, hamster, monkey, porcine, rabbit and yeast.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, pH 7.2, 0.09% Sodium Azide, 50% Glycerol
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant full length human caspase-3 protein with an N-Terminus (His) 6 tag.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
CASP3 / Caspase 3
StandardGeneSymbol :
CASP3
gene family :
Protease
Subfamily :
Cysteine C14
Reactivity :
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Human, Yeast
Usage :
WB (1 µg/ml)
ShortWebDescription :
Caspase 3 antibody LS-C12494 is an unconjugated rabbit polyclonal antibody to Caspase 3 (CASP3) (N-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for WB.
UsageText :
Suitable for use in Western Blot. Western Blot (ECL): 1 ug/ml. A band is seen at ~36kD. Positive control: HeLa Nuclear Extract.
Synonyms :
CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.