product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
CHRM2 / M2 Antibody (aa168-192, clone B8E5) LS-C124189
catalog :
LS-C124189
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B8E5
reactivity :
guinea pig, human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; guinea pig
  • western blot; human
  • western blot; mouse
Cheng Y, Cao A, Zheng J, Wang H, Sun Y, Liu C, et al. Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. Am J Respir Cell Mol Biol. 2014;51:701-8 pubmed publisher
product information
AntibodyID :
127694
AntibodyName :
LS-C124189
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CHRM2 / M2 Antibody (aa168-192, clone B8E5) LS-C124189
Specificity :
Recognizes the pentapeptide VRTVE (aa 168-172) corresponding to the N-terminal part of the second extracellular loop of the human M2 receptor. Species cross-reactivity: rat, mouse and guinea pig.
ClonalityDesc :
Monoclonal
CloneName :
B8E5
AntibodyModification :
Unconjugated
AntigenModification :
aa168-192
PresentationDesc :
PBS, 0.1% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to the second extracellular loop aa168-192, VRTVEDGECYIQFFSNAAVTFGTAI(C) of human muscarinic acetylcholine receptor M2. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Sheep, Panda, Dog, Bovine, Horse, Pig, Guinea pig (100%); Elephant, Bat, Rabbit (96%); Hamster, Opossum, Platypus (92%); Xenopus (88%); Stickleback, Pufferfish, Zebrafish (84%); Turkey, Chicken (80%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
IsotypeName :
IgG2a
Gene :
CHRM2 / M2
StandardGeneSymbol :
CHRM2
gene family :
GPCR
Subfamily :
Acetylcholine
Reactivity :
Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Human, Monkey
Usage :
ELISA (1:50), IF (1:50), IHC, IHC-Fr (1:50), WB (1:50)
ShortWebDescription :
M2 antibody LS-C124189 is an unconjugated mouse monoclonal antibody to M2 (CHRM2) (aa168-192) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IF, IHC and WB. Cited in 1 publication.
UsageText :
Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. ELISA: 1:50. Western Blot: 1:50 under non-reducing conditions. Immunohistochemistry (frozen): 1:50. Immunofluorescence: 1:50.
Synonyms :
CHRM2, 7TM receptor, HM2, M2 muscarinic receptor, M2-mAChR, Muscarinic receptor M2, Muscarinic M2 receptor
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.