This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1) LS-C122115
catalog :
LS-C122115
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JSB-1
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
125573
AntibodyName :
LS-C122115
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1) LS-C122115
Specificity :
Recognizes a conserved cytoplasmic epitope of the plasma membrane-associated 170-180kD glycoprotein human MDR1. The expression is strongly correlated with the degree of multi-drug-resistance (MDR) derived MDR cell lines and human MDR cell lines, including cell lines derived from lung, ovaries and B cell lymphomas. Species cross-reactivity: Chinese hamster. Does not cross-react with mouse or rat.
ClonalityDesc :
Monoclonal
CloneName :
JSB-1
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.1% Sodium Azide, 1% BSA
ImmunogenDesc :
MDR1.
PurificationDesc :
Tissue culture supernatant
RecommendedStorageDesc :
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
IsotypeName :
IgG1
Gene :
ABCB1 / MDR1 / P Glycoprotein
StandardGeneSymbol :
ABCB1
gene family :
Transporter
Subfamily :
ATP-binding cassette - ABCB/MDR
Reactivity :
Hamster, Human
Usage :
Flo (1:10), ICC (1:20), IHC, IHC-Fr, IHC-P, WB (1:10)
ShortWebDescription :
P Glycoprotein antibody LS-C122115 is an unconjugated mouse monoclonal antibody to P Glycoprotein (ABCB1 / MDR1) from human. It is reactive with human and hamster. Validated for Flow, ICC, IHC and WB.
UsageText :
Suitable for use in Flow Cytometry, Western Blot, Immunocytochemistry, and Immunohistochemistry. Flow Cytometry: 1:10 Fix cells in 10% Lysing solution. Western Blot: 1:10. Immunocytochemistry: 1:20 for acetone-fixed cells. Immunohistochemistry: 1:20 for acetone-fixed frozen and formalin-fixed paraffin embedded tissues.
Synonyms :
ABCB1, ABC20, Abcb1b, CLCS, Colchicin sensitivity, CD243, IBD13, gp170, MDR1, Multidrug resistance protein 1, P glycoprotein, P-glycoprotein 1, P-GP, CD243 antigen, PGY1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.