product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
LGALS3 / Galectin 3 Antibody (clone B2C10) LS-C121223
catalog :
LS-C121223
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B2C10
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Mirandola L, Yu Y, Cannon M, Jenkins M, Rahman R, Nguyen D, et al. Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancer. Gynecol Oncol. 2014;135:573-9 pubmed publisher
product information
AntibodyID :
124681
AntibodyName :
LS-C121223
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
LGALS3 / Galectin 3 Antibody (clone B2C10) LS-C121223
Specificity :
Recognizes galectin-3, a 30kD protein. Does not react with Galecin-3C. Inhibits the binding of 125I-labeled galectin-3 to IgE coated on microtiter plates, the galecin-3's hemagglutination activity and galectin-3-induced superoxide production by human neutrophils. This inhibitory activity is probably the result of its disruption of the self-association process. The epitope is found within the first 45 amino acids of galectin-3. Species cross-reactivity: mouse.
ClonalityDesc :
Monoclonal
CloneName :
B2C10
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human galectin-3.
PurificationDesc :
Purified
RecommendedStorageDesc :
May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for up to 1 year at -20°C.
IsotypeName :
IgG1
Gene :
LGALS3 / Galectin 3
StandardGeneSymbol :
LGALS3
Reactivity :
Mouse, Human
Usage :
Flo (1:50), Func, IHC, IHC-Fr (1:50), IHC-P (1:50), WB (1:50)
ShortWebDescription :
Galectin 3 antibody LS-C121223 is an unconjugated mouse monoclonal antibody to Galectin 3 (LGALS3) from human. It is reactive with human and mouse. Validated for Flow, Func, IHC and WB.
UsageText :
Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, Immunoassays and Functional Studies. Flow Cytometry: 1:50. Western Blot: 1:50. Immunohistochemistry (frozen and paraffin): 1:50.
Synonyms :
LGALS3, 35 kd lectin, 35 kDa lectin, CBP35, GAL3, Galactoside-binding protein, GALIG, IgE-binding protein, Laminin-binding protein, Gal-3, GALBP, MAC-2, Mac-2 antigen, L31, MAC2, CBP 35, Galactose-specific lectin 3, Galectin-3, L-31, Lectin L-29
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.