CHEK1 / CHK1 Antibody (phospho-Ser345) LS-C117319 | LifeSpan Biosciences LS-C117319 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

CHEK1 / CHK1 Antibody (phospho-Ser345) LS-C117319

catalog :

LS-C117319

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Wang Z, Førsund M, Trope C, Nesland J, Holm R, Slipicevic A. Evaluation of CHK1 activation in vulvar squamous cell carcinoma and its potential as a therapeutic target in vitro. Cancer Med. 2018;7:3955-3964 pubmed publisher

image

image 1 :

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Chk1 (Phospho-Ser345) Antibody. The picture on the right is blocked with the phospho peptide.

product information

AntibodyID :

120452

AntibodyName :

LS-C117319

TargetSpecies :

Human

Host Species :

Rabbit

Product Name :

CHEK1 / CHK1 Antibody (phospho-Ser345) LS-C117319

Specificity :

Chk1 (Phospho-Ser345) Antibody detects endogenous levels of Chk1 only when phosphorylated at serine345.

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

pSer345

PresentationDesc :

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol

ImmunogenDesc :

Synthetic peptide from human Chk1 around the phosphorylation site of Ser345. (AA Range: 310-359)

PurificationDesc :

Immunoaffinity purified

RecommendedStorageDesc :

Store at -20°C for up to 1 year.

IsotypeName :

IgG

Gene :

CHEK1 / CHK1

StandardGeneSymbol :

CHEK1

gene family :

Protein Kinase

Subfamily :

NIM1

Reactivity :

Mouse, Rat, Human

Usage :

IHC, IHC-P, Peptide-ELISA (1:10000)

ShortWebDescription :

CHK1 antibody LS-C117319 is an unconjugated rabbit polyclonal antibody to CHK1 (CHEK1) (pSer345) from human. It is reactive with human, mouse and rat. Validated for IHC and Peptide-ELISA. Cited in 1 publication.

UsageText :

Western Blot: Predicted MW 54 kDa

Synonyms :

CHEK1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase 1, CHK1, Chk1-S, Protein kinase chk1, Checkpoint kinase-1

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.