This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1) LS-C11667
catalog :
LS-C11667
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JSB-1
reactivity :
human
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
12408
AntibodyName :
LS-C11667
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1) LS-C11667
Specificity :
Recognizes the 170-180kD P-glycoprotein, a plasma membrane associated molecule which is important in mediating resistance to cytotoxic drugs. In normal tissues P-glycoprotein is expressed in liver, kidney, colon, adrenal gland and lung. In malignant conditions increased expression of P-glycoprotein may be associated with multi-drug resistance, and the detection of this can have important consequences for treatment. This clone has also been reported to be suitable for Western blot analysis.
ClonalityDesc :
Monoclonal
CloneName :
JSB-1
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Multi drug resistant Chinese hamster ovary cell line, CHrC5.
PurificationDesc :
Tissue culture supernatant
RecommendedStorageDesc :
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
ABCB1 / MDR1 / P Glycoprotein
StandardGeneSymbol :
ABCB1
gene family :
Transporter
Subfamily :
ATP-binding cassette - ABCB/MDR
Reactivity :
Human
Usage :
Flo, IHC, IHC-Fr (1:10 - 1:20), IHC-P (1:10 - 1:20)
ShortWebDescription :
P Glycoprotein antibody LS-C11667 is an unconjugated mouse monoclonal antibody to human P Glycoprotein (ABCB1 / MDR1 ). Validated for Flow and IHC.
UsageText :
Immunohistology: This product requires protein digestion pre-treatment of paraffin sections e. g. 0.1% pronase, 10 mins.
Synonyms :
ABCB1, ABC20, Abcb1b, CLCS, Colchicin sensitivity, CD243, IBD13, gp170, MDR1, Multidrug resistance protein 1, P glycoprotein, P-glycoprotein 1, P-GP, CD243 antigen, PGY1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.