product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PDGFRB / PDGFR Beta Antibody (Extracellular Domain, clone PR7212) LS-C11443
catalog :
LS-C11443
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PR7212
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Krepela E, Vanickova Z, Hrabal P, Zubal M, Chmielova B, Balaziova E, et al. Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment. Int J Mol Sci. 2021;22: pubmed publisher
product information
AntibodyID :
12184
AntibodyName :
LS-C11443
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PDGFRB / PDGFR Beta Antibody (Extracellular Domain, clone PR7212) LS-C11443
Specificity :
Recognizes the extracellular domain of the human PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. Does not recognize PDGF receptor alpha. PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
ClonalityDesc :
Monoclonal
CloneName :
PR7212
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
PBS with <0.1% sodium azide
ImmunogenDesc :
Human skin fibroblast cell membrane extracts.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
PDGFRB / PDGFR Beta
StandardGeneSymbol :
PDGFRB
gene family :
Protein Kinase
Subfamily :
PDGF Receptor
Reactivity :
Human
NonReactiveSpecies :
Mouse, Rat
Usage :
Flo (25 µg/ml), IF, IHC, IHC-Fr, IHC-P (25 µg/ml), IP, WB
ShortWebDescription :
PDGFR Beta antibody LS-C11443 is an unconjugated mouse monoclonal antibody to human PDGFR Beta (PDGFRB) (Extracellular Domain). Validated for Flow, IF, IHC, IP and WB. Cited in 1 publication.
Synonyms :
PDGFRB, CD140B, Beta pdfgr, Beta type PDGFR, BPDGFR, CD140b antigen, IBGC4, JTK12, PDGF-beta R, PDGF-R-beta, PDGFR, PDGFRbeta, PDGF receptor beta, PDGF-R, PDGFbetaR, PDGFR Beta, PDGFR-1, PDGFR-beta, BetaPDGFR, Pdgf beta-receptor, PDGFR1, PDGFRB/CEV14 fusion gene
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.