product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PTCH1 / Patched 1 Antibody (clone OTI5C7) LS-C114391
catalog :
LS-C114391
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI5C7
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6b
Gu Y, Wang Y, He L, Zhang J, Zhu X, Liu N, et al. Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling. Mol Cancer. 2021;20:132 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C114391 image 1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTCH1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTCH1.
image 2 :
LifeSpan Biosciences LS-C114391 image 2
IHC of paraffin-embedded Adenocarcinoma of colon using anti-PTCH1 mouse monoclonal antibody.
image 3 :
LifeSpan Biosciences LS-C114391 image 3
Anti-PTCH1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTCH1.
product information
AntibodyID :
117158
AntibodyName :
LS-C114391
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PTCH1 / Patched 1 Antibody (clone OTI5C7) LS-C114391
Specificity :
Human PTCH1 / Patched
ClonalityDesc :
Monoclonal
CloneName :
OTI5C7
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant protein fragment corresponding to amino acids 122-436 of human PTCH1 (NP_000255) produced in E. coli.
PurificationDesc :
Protein A/G purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2b
Gene :
PTCH1 / Patched 1
StandardGeneSymbol :
PTCH1
Reactivity :
Human
Usage :
IF (1:100), IHC, IHC-P (1:50), WB (1:500)
ShortWebDescription :
Patched 1 antibody LS-C114391 is an unconjugated mouse monoclonal antibody to human Patched 1 (PTCH1). Validated for IF, IHC and WB.
Synonyms :
PTCH1, NBCCS, Patched 1, Patched homolog 1, Protein patched homolog 1, PTC1, PTCH, PTCH protein +12b, PTCH protein -10, PTCH protein -3,4,5, Patched, Patched protein homolog 1, BCNS, HPE7, Patched homolog, PTC, PTCH protein +4, PTCH11
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.