This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL4R / CD124 Antibody (Extracellular Domain, clone 25463 (49/20)) LS-C11209
catalog :
LS-C11209
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
25463 (49/20)

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
11950
AntibodyName :
LS-C11209
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IL4R / CD124 Antibody (Extracellular Domain, clone 25463 (49/20)) LS-C11209
Specificity :
Recognizes human Interleukin-4 receptor subunit alpha, also known as CD124. CD124 is a 825 amino acid ~90kD type I single pass transmembrane glycoprotein bearing a single domain. Interleukin-4 Receptor form a heterodimeric complex with the, referred to as the IL-4 type-1 complex. The alpha subunit can also form the type-II complex through association with the IL-13 receptor alpha 1 subunit. The IL-4R complex acts as a receptor for both interleukin-4 and interleukin-13. IL-4 R is expressed by B cells, T cells, monocytes and macrophages. Is reported to block human cell surface IL-4 receptor mediated bioactivities induced by IL-4 or IL-13. An ND50 was observed at approximately 5-20 ng/ml in the presence of 0.2 ng/ml of IL-4 using the factor dependant human erythroleukemic cell line, TF-1.
ClonalityDesc :
Monoclonal
CloneName :
25463 (49/20)
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
PBS, 0.5% trehalose
ImmunogenDesc :
Sf 21-derived, recombinant human interleukin 4 receptor, extracellular domain.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
IL4R / CD124
StandardGeneSymbol :
IL4R
gene family :
Interleukin
Reactivity :
Human
Usage :
ELISA (1:500 - 1:2000), Flo (1:20 - 1:80), IHC, IHC-P (1:40 - 1:125), WB (1:250 - 1:1000)
ShortWebDescription :
CD124 antibody LS-C11209 is an unconjugated mouse monoclonal antibody to human CD124 (IL4R) (Extracellular Domain). Validated for ELISA, Flow, IHC and WB.
UsageText :
Western Blot: Will detect human IL-4 R under non-reducing conditions.
Synonyms :
IL4R, CD124, CD124 antigen, IL-4RA, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.