This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PDGFRA / PDGFR Alpha Antibody (Extracellular Domain, clone 35248 (57/20)) LS-C11204
catalog :
LS-C11204
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
35248 (57/20)

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
11945
AntibodyName :
LS-C11204
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PDGFRA / PDGFR Alpha Antibody (Extracellular Domain, clone 35248 (57/20)) LS-C11204
Specificity :
Recognizes the human platelet-derived growth factor receptor alpha, a 1089 amino acid, ~180 kD single pass type I transmembrane glycoprotein. PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulphide-linked PDGF-A and PDGF-B chains. The PDGF-AA, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Whereas PDGF receptor alpha binds all three isoforms with high affinity, PDGF R beta binds PDGF-BB and AB but not PDGF-AA. Both PDGF receptor alpha and beta are members of the class III subfamily of receptor tyrosine kinases. Has been reported for use in functional studies. The ND50 was determined as 0.2-0.6 Âug/ml for blocking 10 ng/ml of PDGF-AA biological activity on a quiescent confluent cell culture of human WS1 cells.
ClonalityDesc :
Monoclonal
CloneName :
35248 (57/20)
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Trehalose
ImmunogenDesc :
Purified recombinant human platelet-derived growth factor (PDGF) receptor alpha (extracellular domain), derived from the insect cell line Sf21.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze/thaw cycles.
IsotypeName :
IgG1
Gene :
PDGFRA / PDGFR Alpha
StandardGeneSymbol :
PDGFRA
gene family :
Protein Kinase
Subfamily :
PDGF Receptor
Reactivity :
Human
Usage :
ELISA (0.5 - 1 µg/ml), IF, IHC, IHC-P (10 - 20 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
PDGFR Alpha antibody LS-C11204 is an unconjugated mouse monoclonal antibody to human PDGFR Alpha (PDGFRA) (Extracellular Domain). Validated for ELISA, IF, IHC and WB.
Synonyms :
PDGFRA, CD140A, CD140a antigen, PDGFalphaR, PDGFR2, PDGFRalpha, AlphaPDGFR, RHEPDGFRA, PDGF receptor alpha, PDGFR-2, PDGFRA/BCR fusion, APDGFR, Pdgf alpha-receptor, PDGF-R-alpha, PDGFR-alpha
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.