product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
DNMT3B Antibody (aa647-696) LS-C111224
catalog :
LS-C111224
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Shen J, Wang C, Li D, Xu T, Myers J, Ashton J, et al. DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. JCI Insight. 2017;2: pubmed publisher
product information
AntibodyID :
113621
AntibodyName :
LS-C111224
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
DNMT3B Antibody (aa647-696) LS-C111224
Specificity :
Human DNMT3B
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa647-696
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide located between aa647-696 of human DNMT3B (Q9UBC3-3, NP_787045). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Chicken, Zebrafish (100%); Platypus, Lizard, Xenopus (90%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Gene :
DNMT3B
BlockingPeptide :
LS-E17770
StandardGeneSymbol :
DNMT3B
gene family :
C5-methyltransferase
Reactivity :
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
Usage :
WB (0.2 - 1 µg/ml)
UsageNotRecommended :
IHC-P
ShortWebDescription :
DNMT3B antibody LS-C111224 is an unconjugated rabbit polyclonal antibody to DNMT3B (aa647-696) from human. It is reactive with human, mouse, rat and other species. Validated for WB. Cited in 1 publication.
UsageText :
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Synonyms :
DNMT3B, DNA MTase HsaIIIB, ICF, ICF1, M.HsaIIIB, DNA methyltransferase HsaIIIB
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.