product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
CXCL10 / IP-10 Antibody LS-C104402
catalog :
LS-C104402
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Luo R, Firat E, Gaedicke S, Guffart E, Watanabe T, Niedermann G. Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment. Clin Cancer Res. 2019;25:7243-7255 pubmed publisher
product information
AntibodyID :
106252
AntibodyName :
LS-C104402
TargetSpecies :
Mouse
Host Species :
Rabbit
Product Name :
CXCL10 / IP-10 Antibody LS-C104402
Specificity :
Mouse IP-10
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS, pH 7.2
ImmunogenType :
Cell extract
ImmunogenDesc :
E.coli derived recombinant Murine IP-0.
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store Lyophilized at room temperature up to 1 month; Reconstituted for up to 2 weeks at 2°C to 8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
ResuspensionLiquidDesc :
sterile ddH20
Gene :
CXCL10 / IP-10
StandardGeneSymbol :
CXCL10
gene family :
Intercrine
Subfamily :
Intercrine alpha
Reactivity :
Mouse
Usage :
ELISA (0.5 - 2 µg/ml), WB (0.1 - 0.2 µg/ml)
ShortWebDescription :
IP-10 antibody LS-C104402 is an unconjugated rabbit polyclonal antibody to mouse IP-10 (CXCL10). Validated for ELISA and WB. Cited in 1 publication.
UsageText :
Immunohistochemistry: This antibody stained colchicine injected mouse brain (including the hippocampus region) tissue. The primary antibody was incubated at 1 mg/ml overnight at 4°C. This was followed by a peroxidase conjugated secondary antibody and then a fluorescein Tyramide Signal Amplification (TSA) reagent. Optimal concentrations and conditions may vary. Neutralization: To yield one-half maximal inhibition [ND] of the biological activity of mIP-10 (100 ng/ml), a concentration of 10 ug/ml of this antibody is required. ELISA: To detect mIP-10 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5-2 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Murine IP-10 (LS-C104391) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant mIP-10. Western Blot: To detect mIP-10 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIP-10 is 1.5-3 ng/lane, under either reducing or non-reducing conditions.
Synonyms :
CXCL10, C-X-C motif chemokine 10, Gamma-IP10, IP-10, Gamma IP10, GIP-10, Mob-1, Small-inducible cytokine B10, Crg-2, IFI10, INP10, SCYB10
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.