product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
p66 / SHC Antibody (N-Terminus) LS-C10119
catalog :
LS-C10119
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; human
Xu X, Zhu X, Ma M, Han Y, Hu C, Yuan S, et al. p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy. Sci Rep. 2016;6:29302 pubmed publisher
Fetoni A, Eramo S, Paciello F, Rolesi R, Samengo D, Paludetti G, et al. The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss. Sci Rep. 2016;6:25450 pubmed publisher
product information
AntibodyID :
10860
AntibodyName :
LS-C10119
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
p66 / SHC Antibody (N-Terminus) LS-C10119
Specificity :
Recognizes the N-terminus of human p66Shc. Species cross-reactivity: mouse, rat and canine.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, pH 7.4, 0.09% sodium azide, PEG, sucrose, 50% glycerol
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to a portion of N-Terminus p66Shc.
PurificationDesc :
Gel filtration
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
p66 / SHC
StandardGeneSymbol :
SHC1
Reactivity :
Human
Usage :
ELISA, WB (0.5 µg/ml)
ShortWebDescription :
SHC antibody LS-C10119 is an unconjugated mouse monoclonal antibody to human SHC (p66) (N-Terminus). Validated for ELISA and WB. Cited in 2 publications.
UsageText :
Suitable for use in ELISA and Western Blot. Western Blot: 0.5 ug/ml for HRP/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer.
Synonyms :
SHC1, p46 shc, p52 shc, SH2 domain protein C1, p66, SHCA, SHC, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.