product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ SDC1 / Syndecan 1 / CD138 Antibody (clone B-A38) LS-B9360
catalog :
LS-B9360
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-A38
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 1
Reference
Solimando A, Da Vià M, Leone P, Borrelli P, Croci G, Tabares P, et al. Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression. Haematologica. 2021;106:1943-1956 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B9360 image 1
Anti-SDC1 / Syndecan 1 / CD138 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
208909
AntibodyName :
LS-B9360
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PathPlus™ SDC1 / Syndecan 1 / CD138 Antibody (clone B-A38) LS-B9360
Specificity :
Recognizes a heparan sulfate rich membrane glycoprotein of 200kD known as Syndecan-1 (CD138). Syndecan functions as a receptor for collagen, fibronectin and thrombospondin. Stains all plasma cells and plasma cell lines. No staining of other leucocytes is seen in peripheral blood or bone marrow, although some ALL cell lines express the antigen weakly. Some staining of epithelial and endothelial cells may be seen in immunohistology.
ClonalityDesc :
Monoclonal
CloneName :
B-A38
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
U266 cell line
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
SDC1 / Syndecan 1 / CD138
StandardGeneSymbol :
SDC1
Reactivity :
Human
Usage :
Flo (1:1), IF, IHC, IHC-Fr (1:100 - 1:500), IHC-P (1:100 - 1:500, 10 µg/ml), WB
ShortWebDescription :
CD138 antibody LS-B9360 is an unconjugated mouse monoclonal antibody to human CD138 (SDC1 / Syndecan 1). Validated for Flow, IF, IHC and WB. Cited in 1 publication.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Immunohistology: This product requires heat pre-treatment. Sodium citrate buffer pH6.0 is recommended for this purpose.
Synonyms :
SDC1, CD138 antigen, SDC, SYND1, Syndecan, Syndecan 1, Syndecan-1, CD138, Syndecan proteoglycan 1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.