This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ EMA / MUC1 Antibody (clone M4H2) LS-B8757
catalog :
LS-B8757
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M4H2

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
187402
AntibodyName :
LS-B8757
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ EMA / MUC1 Antibody (clone M4H2) LS-B8757
Specificity :
Binds with high efficiency to an epitope within the VNTR recombinant repeat peptide region of MUC1 molecule. Reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (but not with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1, but not with completely glycosylated MUC1. Belongs to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross-reactive with normal serum proteins and human tissues of nonepithelial origin.
ClonalityDesc :
Monoclonal
CloneName :
M4H2
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.1% Sodium Azide
ImmunogenDesc :
High molecular weight (>300kD) glycoprotein from human milk-fat globule molecule.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
EMA / MUC1
StandardGeneSymbol :
MUC1
gene family :
Mucin
Reactivity :
Human
Usage :
ELISA, IHC, IHC-Fr, IHC-P (10 µg/ml)
ShortWebDescription :
MUC1 antibody LS-B8757 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
UsageText :
Immunohistochemical and immunofluorescent detection of neoplastic breast epithelium. Works on frozen tissue sections. Construction of immunometric assay for MUC determination. ELISA tests for measurement of unglycosylated and underglycosylated tumor-associated MUC1mucins in human serum. Detection of unglycosylated MUC1. Can be used for immunohistochemical staining of paraffin and frozen sections of breast, lung and ovarian tumor tissues. Staining of paraffin-embedded tissue sections fixed in neutral-buffered formalin.
Synonyms :
MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.