product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ PABPN1 / PABP2 Antibody (Internal, clone EP3001Y) LS-B8482
catalog :
LS-B8482
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EP3001Y
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
Raz V, Dickson G, t Hoen P. Dysfunctional transcripts are formed by alternative polyadenylation in OPMD. Oncotarget. 2017;8:73516-73528 pubmed publisher
  • western blot; mouse; 1:2000; fig 1
  • immunocytochemistry; human
Riaz M, Raz Y, van Putten M, Paniagua Soriano G, Krom Y, Florea B, et al. PABPN1-Dependent mRNA Processing Induces Muscle Wasting. PLoS Genet. 2016;12:e1006031 pubmed publisher
Olie C, van der Wal E, Cikes D, Maton L, de Greef J, Lin I, et al. Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability. Sci Rep. 2020;10:17621 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B8482 image 1
Anti-PABPN1 / PABP2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50-1:100.
product information
AntibodyID :
162960
AntibodyName :
LS-B8482
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ PABPN1 / PABP2 Antibody (Internal, clone EP3001Y) LS-B8482
ClonalityDesc :
Monoclonal
CloneName :
EP3001Y
AntibodyModification :
Unconjugated
AntigenModification :
Internal
PresentationDesc :
Tris-Glycine-NaCl or PBS, pH 7.2-7.4, 40-50% Glycerol, 0.01% sodium azide, 0.05% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to residues in human PABP2.
PurificationDesc :
Tissue culture supernatant
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
PABPN1 / PABP2
StandardGeneSymbol :
PABPN1
Reactivity :
Mouse, Human
Usage :
Flo (1:60), ICC (1:100 - 1:250), IHC, IHC-P (1:50 - 1:100), WB (1:10000 - 1:50000)
ShortWebDescription :
PABP2 antibody LS-B8482 is an unconjugated rabbit monoclonal antibody to PABP2 (PABPN1) (Internal) from human. It is reactive with human and mouse. Validated for Flow, ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Synonyms :
PABPN1, PABP2, Poly(A)-binding protein 2, OPMD, PABII, PABP-2, Poly(A) binding protein 2, Poly(A) binding protein II, Poly(A)-binding protein II, PAB2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.