IHC-plus™ GZMB / Granzyme B Antibody (aa10-59) LS-B7602 | LifeSpan Biosciences LS-B7602 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ GZMB / Granzyme B Antibody (aa10-59) LS-B7602

catalog :

LS-B7602

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 2

Reference
Wanjalla C, McDonnell W, Ram R, Chopra A, Gangula R, Leary S, et al. Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells. Cell Rep Med. 2021;2:100205 pubmed publisher
Nalle S, Zuo L, Ong M, Singh G, Worthylake A, Choi W, et al. Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. J Clin Invest. 2019;129:902-914 pubmed publisher

image

image 1 :

Anti-GZMB / Granzyme B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

image 2 :

Western blot analysis of lysates from NIH/3T3 cells, using Granzyme B Antibody. The lane on the right is blocked with the synthesized peptide.

product information

AntibodyID :

157264

AntibodyName :

LS-B7602

TargetSpecies :

Human

Host Species :

Rabbit

Product Name :

IHC-plus™ GZMB / Granzyme B Antibody (aa10-59) LS-B7602

Specificity :

Granzyme B Antibody detects endogenous levels of total Granzyme B protein.

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

aa10-59

PresentationDesc :

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol

ImmunogenDesc :

Synthetic peptide from human Granzyme B. (AA Range: 8-59)

PurificationDesc :

Immunoaffinity purified

RecommendedStorageDesc :

Store at -20°C for up to 1 year.

IsotypeName :

IgG

Gene :

GZMB / Granzyme B

StandardGeneSymbol :

GZMB

gene family :

Protease

Subfamily :

Serine S1

Reactivity :

Mouse, Rat, Human

Usage :

IHC, IHC-P (1:200), Peptide-ELISA (1:5000), WB (1:500 - 1:1000)

ShortWebDescription :

Granzyme B antibody LS-B7602 is an unconjugated rabbit polyclonal antibody to Granzyme B (GZMB) (aa10-59) from human. It is reactive with human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.

UsageText :

Western Blot: Predicted MW 27 kDa

Synonyms :

GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.