This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ EDA2R / XEDAR Antibody LS-B7278
catalog :
LS-B7278
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
156280
AntibodyName :
LS-B7278
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ EDA2R / XEDAR Antibody LS-B7278
Specificity :
Detects human X-linked ectodermal dysplasia receptor (XEDAR), a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human XEDAR
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
EDA2R / XEDAR
StandardGeneSymbol :
EDA2R
Reactivity :
Human
Usage :
IHC, IHC-P (2.5 µg/ml), WB (0.5 - 2 µg/ml)
ShortWebDescription :
XEDAR antibody LS-B7278 is an unconjugated rabbit polyclonal antibody to human XEDAR (EDA2R). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
UsageText :
Western Blot: Detects a band of approximately 33kD in 293 cell lysates.
Synonyms :
EDA2R, EDA-A2R, EDAA2R, Ectodysplasin A2 receptor, TNFRSF27, XEDAR, EDA-A2 receptor, EDAR2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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