product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ CEACAM8 / CD66b Antibody (clone 80H3) LS-B7134
catalog :
LS-B7134
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
80H3
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human
Liu K, Yang K, Wu B, Chen H, Chen X, Chen X, et al. Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer. Medicine (Baltimore). 2015;94:e1631 pubmed publisher
  • immunohistochemistry; human
Hossain F, Al Khami A, Wyczechowska D, Hernandez C, Zheng L, Reiss K, et al. Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies. Cancer Immunol Res. 2015;3:1236-47 pubmed publisher
Al Khami A, Zheng L, Del Valle L, Hossain F, Wyczechowska D, Zabaleta J, et al. Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells. Oncoimmunology. 2017;6:e1344804 pubmed publisher
Kaewkangsadan V, Verma C, Eremin J, Cowley G, Ilyas M, Satthaporn S, et al. The Differential Contribution of the Innate Immune System to a Good Pathological Response in the Breast and Axillary Lymph Nodes Induced by Neoadjuvant Chemotherapy in Women with Large and Locally Advanced Breast Cancers. J Immunol Res. 2017;2017:1049023 pubmed publisher
product information
AntibodyID :
155379
AntibodyName :
LS-B7134
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ CEACAM8 / CD66b Antibody (clone 80H3) LS-B7134
Specificity :
Reacts with the CGM6 gene product of the carcinoembryonic gene family. This is a 95-100kD GPI anchored molecule. CD66b is expressed strongly by mature granulocytes and metamyelocytes, and weakly by bone marrow myelocytes. CD66b is not expressed by peripheral blood monocytes or lymphocytes.
ClonalityDesc :
Monoclonal
CloneName :
80H3
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide, 0.5% BSA
ImmunogenType :
Cells
ImmunogenDesc :
CML leucocytes.
PurificationDesc :
Protein A purified from tissue culture supernatant
RecommendedStorageDesc :
Upon receipt, aliquot and store at -20°C. May be stored at 4°C for up to 1 month. Avoid freeze/thaw cycles.
IsotypeName :
IgG1
Gene :
CEACAM8 / CD66b
StandardGeneSymbol :
CEACAM8
gene family :
CEA
Reactivity :
Human
Usage :
Flo (1:20 - 1:100), Func, IHC, IHC-Fr (1:25 - 1:100), IHC-P (10 µg/ml), WB
ShortWebDescription :
CD66b antibody LS-B7134 is an unconjugated mouse monoclonal antibody to human CD66b (CEACAM8). Validated for Flow, Func, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 5 x 10^5 cells or 100 ul whole blood.
Synonyms :
CEACAM8, CD66b antigen, Carcinoembryonic antigen CGM6, CD67, CD67 antigen, CGM6, NCA-95, CD66b
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.