product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ RTN4 / Nogo Antibody (aa14-30) LS-B6516
catalog :
LS-B6516
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Kalayil S, Bhogaraju S, Bonn F, Shin D, Liu Y, Gan N, et al. Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination. Nature. 2018;557:734-738 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B6516 image 1
Anti-RTN4 / Nogo antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
product information
AntibodyID :
151985
AntibodyName :
LS-B6516
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ RTN4 / Nogo Antibody (aa14-30) LS-B6516
Specificity :
This recognizes Nogo-A (approx. 220 kD)and Nogo-B2 and B1 (approx. 50 kD and 48 kD in human and 43 kD and 41 kD in mouse and rat, respectively).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa14-30
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenDesc :
A synthetic sequence corresponding to amino acids 14-30 (DSPPRPQPAFKYQFVRE) of human Nogo-B was used as the immunogen, GenBank no. AAG40878.1 AF320999_1. Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Pig (100%); Bovine (94%); Mouse, Rat, Bat, Dog (88%); Opossum (82%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Gene :
RTN4 / Nogo
StandardGeneSymbol :
RTN4
gene family :
Reticulon
Reactivity :
Mouse, Rat, Pig, Human, Monkey
Usage :
IHC, IHC-P (1:100), WB (1:500 - 1:2000)
ShortWebDescription :
Nogo antibody LS-B6516 is an unconjugated rabbit polyclonal antibody to Nogo (RTN4) (aa14-30) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
This antibody recognizes Nogo-A (approximately 220 kD)and Nogo-B2 and B1 (approximately 50 kD and 48 kD in human and 43 kD and 41 kD in mouse and rat, respectively).
Synonyms :
RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.