IHC-plus™ EPM2A / Laforin Antibody (aa131-144) LS-B6474 | LifeSpan Biosciences LS-B6474 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ EPM2A / Laforin Antibody (aa131-144) LS-B6474

catalog :

LS-B6474

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Chambers J, Thongtharb A, Shiga T, Azakami D, Saito M, Sato M, et al. Accumulation of Laforin and Other Related Proteins in Canine Lafora Disease With EPM2B Repeat Expansion. Vet Pathol. 2018;55:543-551 pubmed publisher

image

image 1 :

Antibody (0.1 ug/ml) staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

image 2 :

Anti-EPM2A antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

product information

AntibodyID :

151943

AntibodyName :

LS-B6474

TargetSpecies :

Human

Host Species :

Goat

Product Name :

IHC-plus™ EPM2A / Laforin Antibody (aa131-144) LS-B6474

Specificity :

Human EPM2A. This antibody is expected to recognize isoform a (NP_005661.1) only.

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

aa131-144

PresentationDesc :

TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA

ImmunogenDesc :

Peptide with sequence C-EATGHTNEMKHTTD, from the internal region of the protein sequence according to NP_005661.1.

PurificationDesc :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

RecommendedStorageDesc :

Aliquot and store at -20°C. Avoid freeze-thaw cycles.

Gene :

EPM2A / Laforin

BlockingPeptide :

LS-E26732

StandardGeneSymbol :

EPM2A

gene family :

Protein Phosphatase

Subfamily :

Laforin

Reactivity :

Rabbit, Mouse, Dog, Bovine, Rat, Pig, Bat, Human, Monkey

Usage :

IHC, IHC-P (2.5 - 3.75 µg/ml), Peptide-ELISA (1:16000), WB (0.1 - 0.3 µg/ml)

ShortWebDescription :

Laforin antibody LS-B6474 is an unconjugated goat polyclonal antibody to Laforin (EPM2A) (aa131-144) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.

UsageText :

Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx. 38kD band observed in Human Brain (Cerebellum), Mouse Brain and Rat Brain lysates (calculated MW of 37.2kD according to NP_005661.1). Recommended concentration: 0.1-0.3 ug/ml.

Synonyms :

EPM2A, EPM2, LAFPTPase, LDE, Lafora PTPase, MELF, Laforin, LD

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.