This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ UNG / Uracil DNA Glycosylase Antibody (aa281-298) LS-B6459
catalog :
LS-B6459
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
151928
AntibodyName :
LS-B6459
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ UNG / Uracil DNA Glycosylase Antibody (aa281-298) LS-B6459
Specificity :
The synthetic peptide sequence used for immunogen is 100% conserved between UNG1 and UNG2. Thus recognizes both UNG1 and UNG2. As UNG1 and UNG2 are not resolved as two species in gel electrophoresis (Huag et al., 1998), they are indistinguishable by western blot. The observed molecular weight of UNG (UNG1 and UNG2) on western blots may vary: 26 kD, 27.5 kD, 31 kD, and 38 kD forms have been described (Bharati et al., 1998; Slupphaug et al., 1993). Please see Kruman et al. (Fig. 1D, 2004) for an example of western blot in rat. This specificity of this has been validated by antisense UNG oligonucleotide (Kruman et al. 2004).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa281-298
PresentationDesc :
PBS, 0.05% Sodium Azide, 0.05% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide sequence CRHFSKTNELLQKSGKKP corresponding to amino acids 281-298 of human UNG1 (NP003353.1) and amino acids 290-307 of human UNG2 (NP 550433.1). The peptide sequence used for immunogen is highly conserved between mammalian and invertabrates. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Gibbon, Marmoset, Mouse, Dog, Bat, Bovine, Horse, Rabbit, Turkey, Chicken (94%); Rat, Hamster, Elephant, Panda, Pig, Platypus (89%); Zebrafish (83%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
UNG / Uracil DNA Glycosylase
StandardGeneSymbol :
UNG
Reactivity :
Human
Usage :
IHC, IHC-P (10 µg/ml), WB (2 µg/ml)
ShortWebDescription :
Uracil DNA Glycosylase antibody LS-B6459 is an unconjugated rabbit polyclonal antibody to human Uracil DNA Glycosylase (UNG) (aa281-298). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Synonyms :
UNG, DGU, HIGM4, HIGM5, Uracil-DNA glycosylase, UNG1, UNG2, UDG, UNG15
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.