product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ GJB2 / CX26 / Connexin 26 Antibody (C-Terminus) LS-B6429
catalog :
LS-B6429
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse
Kamiya K, Yum S, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, et al. Assembly of the cochlear gap junction macromolecular complex requires connexin 26. J Clin Invest. 2014;124:1598-607 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B6429 image 1
Anti-GJB2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
151880
AntibodyName :
LS-B6429
TargetSpecies :
Mouse
Host Species :
Mouse
Product Name :
IHC-plus™ GJB2 / CX26 / Connexin 26 Antibody (C-Terminus) LS-B6429
Specificity :
Detects the Connexin 26 protein. No cross-reactivity with the closely related Connexin 30 protein has been observed.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, pH 7.4, 0.09% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 13 AA synthetic peptide derived from the C-Terminus of mouse Connexin 26 protein. This mouse sequence differs from the rat sequence by a single amino acid and from the human sequence by two (non-consecutive) amino acids.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a,k
Gene :
GJB2 / CX26 / Connexin 26
StandardGeneSymbol :
GJB2
gene family :
Ion Channel
Subfamily :
Connexin
Reactivity :
Mouse, Rat, Human
Usage :
ELISA (1:500), IF (1:60 - 1:250), IHC, IHC-P (10 µg/ml), WB (1:250 - 1:1000)
ShortWebDescription :
Connexin 26 antibody LS-B6429 is an unconjugated mouse monoclonal antibody to Connexin 26 (GJB2 / CX26) (C-Terminus) from mouse. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB. Cited in 1 publication.
UsageText :
Antibody reactivity was confirmed by Western blotting using lysates derived from mouse liver, rat liver and rat brain. Antibody was tested for IHC-P using human FFPE tissues.
Synonyms :
GJB2, Connexin 26, Connexin-26, DFNB1A, DFNA3, DFNB1, Gap junction protein beta 2, KID, HID, PPK, NSRD1, CX26, DFNA3A
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.