product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ CYBB / NOX2 / gp91phox Antibody (clone 48) LS-B6247
catalog :
LS-B6247
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
48
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human
Brandt M, Garlapati V, Oelze M, Sotiriou E, Knorr M, Kröller Schön S, et al. NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy. Sci Rep. 2016;6:32554 pubmed publisher
Sürün D, Schwäble J, Tomasovic A, Ehling R, Stein S, Kurrle N, et al. High Efficiency Gene Correction in Hematopoietic Cells by Donor-Template-Free CRISPR/Cas9 Genome Editing. Mol Ther Nucleic Acids. 2018;10:1-8 pubmed publisher
Seredenina T, Sorce S, Herrmann F, Ma Mulone X, Plastre O, Aguzzi A, et al. Decreased NOX2 expression in the brain of patients with bipolar disorder: association with valproic acid prescription and substance abuse. Transl Psychiatry. 2017;7:e1206 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B6247 image 1
Anti-NOX2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
150112
AntibodyName :
LS-B6247
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ CYBB / NOX2 / gp91phox Antibody (clone 48) LS-B6247
ClonalityDesc :
Monoclonal
CloneName :
48
AntibodyModification :
Unconjugated
PresentationDesc :
20 mM Tris, 150 mM sodium chloride, pH 8.0, 0.1% sodium azide. Sourced from tissue culture supernatant.
ImmunogenDesc :
Purified cytochrome B558 preparation.
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
CYBB / NOX2 / gp91phox
StandardGeneSymbol :
CYBB
Reactivity :
Human
Usage :
IHC, IHC-P (10 µg/ml), WB
ShortWebDescription :
Gp91phox antibody LS-B6247 is an unconjugated mouse monoclonal antibody to human gp91phox (CYBB / NOX2). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Synonyms :
CYBB, Chronic granulomatous disease, CGD91-phox, Cytochrome b558 subunit beta, Cytochrome b(558) subunit beta, gp91-1, gp91-PHOX, p22 phagocyte B-cytochrome, AMCBX2, CGD, Cytochrome b-245 heavy chain, gp91PHOX, NADPH oxidase 2, NOX2, p91-PHOX
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.