product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M2F12) LS-B6232
catalog :
LS-B6232
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M2F12
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Wang H, Shah C, Hu L, Huang W, Platanias L, Eklund E. An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice. J Biol Chem. 2020;295:9663-9675 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B6232 image 1
Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
150097
AntibodyName :
LS-B6232
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M2F12) LS-B6232
Specificity :
Reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1a. Reacts with human, rat, and mouse receptor. Other species untested.
ClonalityDesc :
Monoclonal
CloneName :
M2F12
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, pH 7.4
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C to -70°C for up to 1 year. Aliquot to avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
FGFR1 / FGF Receptor 1
StandardGeneSymbol :
FGFR1
gene family :
Protein Kinase
Subfamily :
FGF Receptor
Reactivity :
Mouse, Rat, Human
Usage :
IHC, IHC-Fr, IHC-P (10 µg/ml), IP, WB (1 µg/ml)
ShortWebDescription :
FGF Receptor 1 antibody LS-B6232 is an unconjugated mouse monoclonal antibody to FGF Receptor 1 (FGFR1) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1. Immunoprecipitation: native, nuclear, recombinant, and ligand-labeled FGFr1. Immunohistochemistry: frozen sections of human glioblastomas, paraformaldehyde fixed cells and nuclei, human myocardial biopsies, FFPE human tissues.
Synonyms :
FGFR1, BFGF receptor, BFGF-R, BFGF-R-1, CD331, Cek1, CD331 antigen, FGFR1/PLAG1 fusion, FLT2, Fgf-flg, FGFBR, FGFR-1, Fms-like tyrosine kinase 2, HBGFR, HH2, Hydroxyaryl-protein kinase, FGF receptor 1, Fms-related tyrosine kinase 2, Proto-oncogene c-Fgr, BFGFR, CEK, FLT-2, HBGF receptor, KAL2, OGD
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.