product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ FOLR1 / Folate Receptor Alpha Antibody (aa179-228) LS-B5727
catalog :
LS-B5727
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
  • immunohistochemistry; human
Cai L, Michelakos T, Ferrone C, Zhang L, Deshpande V, Shen Q, et al. Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma. Oncotarget. 2017;8:37646-37656 pubmed publisher
  • flow cytometry; mouse
Liang X, Luo M, Wei X, Ma C, Yang Y, Shao B, et al. A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy. Oncotarget. 2016;7:52207-52217 pubmed publisher
Pierce J, Cho S, Nag S, Zeh R, Jeon J, Holt D, et al. Folate Receptor Overexpression in Human and Canine Meningiomas-Immunohistochemistry and Case Report of Intraoperative Molecular Imaging. Neurosurgery. 2019;85:359-368 pubmed publisher
Keating J, Runge J, Singhal S, Nims S, Venegas O, Durham A, et al. Intraoperative near-infrared fluorescence imaging targeting folate receptors identifies lung cancer in a large-animal model. Cancer. 2017;123:1051-1060 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B5727 image 1
Anti-Folate Binding Protein antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
140333
AntibodyName :
LS-B5727
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ FOLR1 / Folate Receptor Alpha Antibody (aa179-228) LS-B5727
Specificity :
Human FOLR1
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa179-228
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide located between aa179-228 of human FOLR1 (P15328, NP_000793). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Galago, Mouse, Rat, Hamster, Dog, Bat, Rabbit, Horse (100%); Gibbon, Marmoset, Elephant, Bovine, Pig, Opossum, Guinea pig (92%); Zebra finch (85%); Chicken (84%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
FOLR1 / Folate Receptor Alpha
BlockingPeptide :
LS-E15240
StandardGeneSymbol :
FOLR1
Reactivity :
Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Human
Usage :
IHC, IHC-P (5 µg/ml), WB (0.2 - 1 µg/ml)
ShortWebDescription :
Folate Receptor Alpha antibody LS-B5727 is an unconjugated rabbit polyclonal antibody to Folate Receptor Alpha (FOLR1) (aa179-228) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
UsageText :
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:62500.
Synonyms :
FOLR1, Adult folate-binding protein, FBP, Folate receptor alpha, KB cells FBP, Folate binding protein, Folate receptor 1, Folate receptor 1 (adult), Folate receptor, adult, FOLR, FR-alpha
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.