product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ SIRT6 / Sirtuin 6 Antibody (aa56-105) LS-B5589
catalog :
LS-B5589
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Harlan B, Killoy K, Pehar M, Liu L, Auwerx J, Vargas M. Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020;327:113219 pubmed publisher
Gorczyca G, Wartalski K, Tabarowski Z, Duda M. Effects of vinclozolin exposure on the expression and activity of SIRT1 and SIRT6 in the porcine ovary. J Physiol Pharmacol. 2019;70: pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B5589 image 1
Anti-SIRT6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
140195
AntibodyName :
LS-B5589
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ SIRT6 / Sirtuin 6 Antibody (aa56-105) LS-B5589
Specificity :
Human SIRT6
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa56-105
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide located between aa56-105 of human SIRT6 (Q8N6T7, NP_057623). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Hamster, Elephant, Dog, Bat, Pig, Opossum (100%); Gibbon, Rat, Bovine, Horse, Guinea pig, Platypus (92%); Turkey, Zebra finch, Chicken, Xenopus (84%).
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
SIRT6 / Sirtuin 6
BlockingPeptide :
LS-E11351
StandardGeneSymbol :
SIRT6
Reactivity :
Mouse, Dog, Hamster, Pig, Bat, Human, Monkey
Usage :
IHC, IHC-P (10 µg/ml), WB (1.25 µg/ml)
ShortWebDescription :
Sirtuin 6 antibody LS-B5589 is an unconjugated rabbit polyclonal antibody to Sirtuin 6 (SIRT6) (aa56-105) from human. It is reactive with human, mouse, bat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Synonyms :
SIRT6, SIR2-like protein 6, Sirtuin type 6, SIR2L6, Sir2-related protein type 6, Sirtuin 6
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.