product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ FBN1 / Fibrillin 1 Antibody (aa45-450, clone 26) LS-B5512
catalog :
LS-B5512
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
26
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Lian X, Bond J, Bharathy N, Boudko S, Pokidysheva E, Shern J, et al. Defining the Extracellular Matrix of Rhabdomyosarcoma. Front Oncol. 2021;11:601957 pubmed publisher
Che X, Jian F, Wang Y, Zhang J, Shen J, Cheng Q, et al. FBXO2 Promotes Proliferation of Endometrial Cancer by Ubiquitin-Mediated Degradation of FBN1 in the Regulation of the Cell Cycle and the Autophagy Pathway. Front Cell Dev Biol. 2020;8:843 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B5512 image 1
Anti-FBN1 / Fibrillin 1 antibody IHC of human prostate, extra cellular matrix. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
140061
AntibodyName :
LS-B5512
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ FBN1 / Fibrillin 1 Antibody (aa45-450, clone 26) LS-B5512
Specificity :
Recognizes human Fibrillin-1. Epitope mapping studies identify the binding site of this antibody to amino terminal end of the molecule, between amino acid residues 45 and 450. Species cross-reactivity: Human, chicken and bovine.
ClonalityDesc :
Monoclonal
CloneName :
26
AntibodyModification :
Unconjugated
AntigenModification :
aa45-450
PresentationDesc :
PBS, pH 7.6, 0.09% Sodium Azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Human Fibrillin-1
PurificationDesc :
Purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
FBN1 / Fibrillin 1
StandardGeneSymbol :
FBN1
Reactivity :
Chicken, Bovine, Human
Usage :
ELISA, IF, IHC, IHC-P (10 µg/ml), IP, WB
ShortWebDescription :
Fibrillin 1 antibody LS-B5512 is an unconjugated mouse monoclonal antibody to Fibrillin 1 (FBN1) (aa45-450) from human. It is reactive with human, bovine and chicken. Validated for ELISA, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
UsageText :
Suitable for use in Western Blot, Immunofluorescence, Immunoprecipitation and ELISA.
Synonyms :
FBN1, ACMICD, Fibrillin 1, Fibrillin-1, FBN, ECTOL1, GPHYSD2, MASS, MFS1, OCTD, SSKS, WMS2, Fibrillin 1 (Marfan syndrome), Fibrillin 15, SGS, WMS
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.