product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ Mannose Receptor / CD206 Antibody (clone 5C11) LS-B5474
catalog :
LS-B5474
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5C11
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Wu H, Han Y, Rodriguez Sillke Y, Deng H, Siddiqui S, Treese C, et al. Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages. EMBO Mol Med. 2019;11:e10698 pubmed publisher
Furukoji E, Gi T, Yamashita A, Moriguchi Goto S, Kojima M, Sugita C, et al. CD163 macrophage and erythrocyte contents in aspirated deep vein thrombus are associated with the time after onset: a pilot study. Thromb J. 2016;14:46 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B5474 image 1
MRC1 monoclonal antibody clone 5C11. Western blot of MRC1 expression in human pancreas.
image 2 :
LifeSpan Biosciences LS-B5474 image 2
Detection limit for recombinant GST tagged MRC1 is approximately 0.03 ng/ml as a capture antibody.
image 3 :
LifeSpan Biosciences LS-B5474 image 3
Anti-CD206 antibody IHC of human lung, macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
140023
AntibodyName :
LS-B5474
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ Mannose Receptor / CD206 Antibody (clone 5C11) LS-B5474
Specificity :
Human MRC1
ClonalityDesc :
Monoclonal
CloneName :
5C11
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4
ImmunogenType :
Recombinant protein
ImmunogenDesc :
MRC1 (NP_002429, 22 aa ~ 131 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
PurificationDesc :
Purified from ascites by Protein A
RecommendedStorageDesc :
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
IsotypeName :
IgG1,k
Gene :
Mannose Receptor / CD206
StandardGeneSymbol :
MRC1
Reactivity :
Human
Usage :
ELISA, IHC, IHC-P (5 µg/ml), WB (1:500 - 1:1000)
ShortWebDescription :
CD206 antibody LS-B5474 is an unconjugated mouse monoclonal antibody to human CD206 (Mannose Receptor). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
UsageText :
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western blot using tissue lysates and the recombinant protein used as the immunogen.
Synonyms :
MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.