product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ PECAM-1 / CD31 Antibody LS-B4737
catalog :
LS-B4737
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
Yuan K, Shao N, Hennigs J, Discipulo M, Orcholski M, Shamskhou E, et al. Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension. Am J Pathol. 2016;186:2500-14 pubmed publisher
Yellamilli A, Ren Y, McElmurry R, Lambert J, Gross P, Mohsin S, et al. Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion. FASEB J. 2020;34:5642-5657 pubmed publisher
Falke L, He N, Chuva de Sousa Lopes S, Broekhuizen R, Lyons K, Nguyen T, et al. FoxD1-driven CCN2 deletion causes axial skeletal deformities, pulmonary hypoplasia, and neonatal asphyctic death. J Cell Commun Signal. 2020;: pubmed publisher
Osmanagic Myers S, Kiss A, Manakanatas C, Hamza O, Sedlmayer F, Szabo P, et al. Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. J Clin Invest. 2019;129:531-545 pubmed publisher
Ungaro F, Tacconi C, Massimino L, Corsetto P, Correale C, Fonteyne P, et al. MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in Mice. Gastroenterology. 2017;153:1363-1377.e6 pubmed publisher
Orcholski M, Khurshudyan A, Shamskhou E, Yuan K, Chen I, Kodani S, et al. Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2017;313:L252-L266 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B4737 image 1
Anti-CD31 antibody IHC of human lung, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
124429
AntibodyName :
LS-B4737
TargetSpecies :
Mouse
Host Species :
Rabbit
Product Name :
PathPlus™ PECAM-1 / CD31 Antibody LS-B4737
Specificity :
c-terminal
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
10 mM PBS, pH 7.6, 15 mM Sodium Azide, 0.2% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to C-Terminus of mouse CD31 protein.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
Gene :
PECAM-1 / CD31
StandardGeneSymbol :
PECAM1
Reactivity :
Mouse, Human
Usage :
IHC, IHC-P (10 µg/ml)
ShortWebDescription :
CD31 antibody LS-B4737 is an unconjugated rabbit polyclonal antibody to CD31 (PECAM-1) from mouse. It is reactive with human and mouse. Validated for IHC. Cited in 8 publications.
Synonyms :
PECAM1, CD31, CD31 antigen, EndoCAM, PECA1, PECAM-1, GPIIA
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.