product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ AGTR1 / AT1 Receptor Antibody LS-B4614
catalog :
LS-B4614
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Ma Y, Xia Z, Ye C, Lu C, Zhou S, Pan J, et al. AGTR1 promotes lymph node metastasis in breast cancer by upregulating CXCR4/SDF-1α and inducing cell migration and invasion. Aging (Albany NY). 2019;11:3969-3992 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B4614 image 1
Western blot of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 ug/ml.
image 2 :
LifeSpan Biosciences LS-B4614 image 2
Anti-AGTR1 antibody IHC of human heart, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
image 3 :
LifeSpan Biosciences LS-B4614 image 3
Immunofluorescence of AGTR1 in Mouse Kidney cells with AGTR1 antibody at 20 ug/ml.
product information
AntibodyID :
124280
AntibodyName :
LS-B4614
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ AGTR1 / AT1 Receptor Antibody LS-B4614
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS containing 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 16 AA synthetic peptide near the center of human AGTR1. The immunogen is located within aa 210-260 of AGTR1.
PurificationDesc :
Peptide Column Affinity Chromatography
RecommendedStorageDesc :
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
AGTR1 / AT1 Receptor
BlockingPeptide :
LS-E30774
StandardGeneSymbol :
AGTR1
gene family :
GPCR
Subfamily :
Angiotensin
Reactivity :
Mouse, Rat, Human
Usage :
ELISA, IF, IHC, IHC-P (5 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
AT1 Receptor antibody LS-B4614 is an unconjugated rabbit polyclonal antibody to AT1 Receptor (AGTR1) from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
UsageText :
AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Western Blot:
Synonyms :
AGTR1, AG2S, AGTR1A, AGTR1B, Angiotensin II type-1 receptor, Ang ii receptor type 1a, Angiotensin receptor 1, Angiotensin receptor 1a, Angiotensin receptor 1B, AT1R, AT1 receptor, At1a receptor, AT1B, AT1AR, AT2R1, AT2R1A, AT2R1B, HAT1R, AT1, At1a, At1b receptor, AT1BR, Type-1 angiotensin II receptor
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.