This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ PACE4 / PCSK6 Antibody (aa637-648) LS-B4377
catalog :
LS-B4377
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
120214
AntibodyName :
LS-B4377
TargetSpecies :
Human
Host Species :
Goat
Product Name :
IHC-plus™ PACE4 / PCSK6 Antibody (aa637-648) LS-B4377
Specificity :
Human PCSK6 / PACE4. This antibody is expected to recognize reported isoforms a, b, g and h (NP_002561.1; NP_612192.1; NP_612193.1; NP_612194.1 resp.).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa637-648
PresentationDesc :
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
ImmunogenDesc :
Peptide with sequence C-YHTFSAHQSRSR, from the internal region of the protein sequence according to NP_002561.1NP_612192.1NP_612195.1NP_612197.1NP_612196.1NP_612198.2NP_612193.1NP_612194.1.
PurificationDesc :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Gene :
PACE4 / PCSK6
BlockingPeptide :
LS-E26859
StandardGeneSymbol :
PCSK6
gene family :
Protease
Subfamily :
Serine S8
Reactivity :
Rabbit, Human
Usage :
IHC, IHC-P (5 µg/ml), Peptide-ELISA (1:32000)
ShortWebDescription :
PCSK6 antibody LS-B4377 is an unconjugated goat polyclonal antibody to PCSK6 (PACE4) (aa637-648) from human. It is reactive with human and rabbit. Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
UsageText :
Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Preliminary experiments gave an approx 40-45 kD band in Human Brain (Cerebellum) lysates after 0.2 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 106 kD according to NP_002561.1. The 40-45 kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?
Synonyms :
PCSK6, PACE4, SPC4
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.