product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ SLC7A11 / XCT Antibody (aa215-229) LS-B4345
catalog :
LS-B4345
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 1
Reference |
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Polewski M, Reveron Thornton R, Cherryholmes G, Marinov G, Cassady K, Aboody K. Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance. Mol Cancer Res. 2016;14:1229-1242 pubmed
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image
image 1 :

Antibody (0.02 ug/ml) staining of Human Spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
image 2 :

Anti-SLC7A11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
product information
AntibodyID :
120182
AntibodyName :
LS-B4345
TargetSpecies :
Human
Host Species :
Goat
Product Name :
PathPlus™ SLC7A11 / XCT Antibody (aa215-229) LS-B4345
Specificity :
Human SLC7A11.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa215-229
PresentationDesc :
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
ImmunogenDesc :
Peptide with sequence C-KGQTQNFKDAFSGRD, from the internal region of the protein sequence according to NP_055146.1.
PurificationDesc :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Gene :
SLC7A11 / XCT
BlockingPeptide :
LS-E26198
StandardGeneSymbol :
SLC7A11
gene family :
Transporter
Subfamily :
Cationic amino acid transporter
Reactivity :
Human, Monkey
Usage :
IF (10 µg/ml), IHC, IHC-P (3.75 µg/ml), Peptide-ELISA (1:128000), WB (0.03 - 0.3 µg/ml)
ShortWebDescription :
XCT antibody LS-B4345 is an unconjugated goat polyclonal antibody to XCT (SLC7A11) (aa215-229) from human. It is reactive with human and monkey. Validated for IF, IHC, Peptide-ELISA and WB. Cited in 1 publication.
Synonyms :
SLC7A11, CCBR1, Cystine/glutamate transporter, XCT, SLC711
SalesRegion :
Worldwide
more info or order :
company information

LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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