product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ MDM4 / MDMX Antibody (aa 2-185, clone 2D10F4) LS-B4097
catalog :
LS-B4097
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2D10F4
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 3e
  • western blot; human; loading ...; fig 2a
Liu T, Xiong J, Yi S, Zhang H, Zhou S, Gu L, et al. FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2. Oncogene. 2017;36:1678-1686 pubmed publisher
  • western blot; human
Liu T, Zhang H, Xiong J, Yi S, Gu L, Zhou M. Inhibition of MDM2 homodimerization by XIAP IRES stabilizes MDM2, influencing cancer cell survival. Mol Cancer. 2015;14:65 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B4097 image 1
Anti-MDM4 / MDMX antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
product information
AntibodyID :
116949
AntibodyName :
LS-B4097
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ MDM4 / MDMX Antibody (aa 2-185, clone 2D10F4) LS-B4097
Specificity :
Human
ClonalityDesc :
Monoclonal
CloneName :
2D10F4
AntibodyModification :
Unconjugated
AntigenModification :
aa 2-185
PresentationDesc :
Ascitic fluid, 0.03% sodium azide
ImmunogenDesc :
Purified recombinant fragment of human MDM4 expressed in E. Coli.
PurificationDesc :
Ascites
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C.
IsotypeName :
IgG1
Gene :
MDM4 / MDMX
StandardGeneSymbol :
MDM4
Reactivity :
Human
Usage :
ELISA (1:10000), IF (1:200 - 1:1000), IHC, IHC-P (1:200), WB (1:100 - 1:500)
ShortWebDescription :
MDMX antibody LS-B4097 is an unconjugated mouse monoclonal antibody to human MDMX (MDM4) (aa 2-185). Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Synonyms :
MDM4, Mdm2-like p53-binding protein, MDMX, HDMX, MRP1, p53-binding protein Mdm4, Protein Mdm4, Double minute 4 protein, MDM4-related protein 1, Protein Mdmx
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.