This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ NR1I2 / PXR Antibody (aa406-420) LS-B3968
catalog :
LS-B3968
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
114883
AntibodyName :
LS-B3968
TargetSpecies :
Human
Host Species :
Goat
Product Name :
IHC-plus™ NR1I2 / PXR Antibody (aa406-420) LS-B3968
Specificity :
Human NR1I2 / PXR. This antibody is expected to recognize all reported isoforms (NP_071285.1; NP_148934.1; NP_003880.3).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa406-420
PresentationDesc :
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
ImmunogenDesc :
Peptide with sequence EQFAITLKSYIECNR, from the internal region of the protein sequence according to NP_003880.3NP_071285.1NP_148934.1.
PurificationDesc :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
RecommendedStorageDesc :
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Gene :
NR1I2 / PXR
BlockingPeptide :
LS-E26983
StandardGeneSymbol :
NR1I2
gene family :
NHR
Subfamily :
NR1 Thyroid hormone-like
Reactivity :
Human
Usage :
IHC, IHC-P (3.75 µg/ml), Peptide-ELISA (1:4000), WB (1 - 3 µg/ml)
ShortWebDescription :
PXR antibody LS-B3968 is an unconjugated goat polyclonal antibody to human PXR (NR1I2) (aa406-420). Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
UsageText :
Peptide ELISA: antibody detection limit dilution 1:4000. Western Blot: Approx. 48kD band observed in lysates of cell line HepG2 (calculated MW of 49.8kD according to NP_003880.3). Recommended concentration: 1-3 ug/ml. An additional band of unknown identity was also consistently observed at 35kD. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?
Synonyms :
NR1I2, BXR, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, PARq, PRR, PXR, Pregnane X receptor, ONR1, SAR, SXR
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.