product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ IL23A / IL-23 p19 Antibody (clone HLT2736) LS-B3708
catalog :
LS-B3708
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HLT2736
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 3
Reference
Muehlbauer S, Lima H, Goldman D, Jacobson L, Rivera J, Goldberg M, et al. Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. Am J Pathol. 2010;177:735-43 pubmed publisher
Katsifis G, Rekka S, Moutsopoulos N, Pillemer S, Wahl S. Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis. Am J Pathol. 2009;175:1167-77 pubmed publisher
Ohyama H, Kato Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, et al. The involvement of IL-23 and the Th17 pathway in periodontitis. J Dent Res. 2009;88:633-8 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B3708 image 1
Linker-free, recombinant human IL-23 was resolved by electrophoresis, transferred to nitrocellulose and probed with the anti-IL23 p19 specific antibody HLT2736 antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a ch.
image 2 :
LifeSpan Biosciences LS-B3708 image 2
Anti-IL-23 p19 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
product information
AntibodyID :
111065
AntibodyName :
LS-B3708
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PathPlus™ IL23A / IL-23 p19 Antibody (clone HLT2736) LS-B3708
Specificity :
Human recombinant p40 and p19 with elastin linker
ClonalityDesc :
Monoclonal
CloneName :
HLT2736
AntibodyModification :
Unconjugated
PresentationDesc :
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide. Sourced in TCS.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human IL23A / IL-23.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Store undiluted.
IsotypeName :
IgG1
Gene :
IL23A / IL-23 p19
StandardGeneSymbol :
IL23A
gene family :
Interleukin
Reactivity :
Human
Usage :
IHC, IHC-P (10 µg/ml), WB
ShortWebDescription :
IL-23 p19 antibody LS-B3708 is an unconjugated mouse monoclonal antibody to human IL-23 p19 (IL23A). Validated for IHC and WB. Cited in 3 publications.
UsageText :
Immunohistochemistry: LS-B3708 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3708 was determined to be 10 ug/ml.
Synonyms :
IL23A, IL-23 subunit alpha, IL-23A, Interleukin 23 p19 subunit, Interleukin-23 subunit alpha, IL23P19, Interleukin-23 subunit p19, p19, SGRF, IL-23, IL-23 p19, IL-23-A, IL-23p19
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.