product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PathPlus™ EGR2 Antibody (aa397-446) LS-B3577
catalog :
LS-B3577
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Schizas N, Konig N, Andersson B, Vasylovska S, Hoeber J, Kozlova E, et al. Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor. Cell Tissue Res. 2018;372:493-505 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B3577 image 1
Anti-EGR2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
109463
AntibodyName :
LS-B3577
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PathPlus™ EGR2 Antibody (aa397-446) LS-B3577
Specificity :
Human EGR2
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa397-446
PresentationDesc :
PBS, 0.09% sodium azide, 2% sucrose
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide located between aa397-446 of human EGR2 (P11161, NP_000390). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Bovine (100%); Rat, Hamster, Elephant, Panda, Dog, Rabbit, Pig, Guinea pig (92%); Galago, Horse (85%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
EGR2
BlockingPeptide :
LS-E10864
StandardGeneSymbol :
EGR2
gene family :
Transcription factor
Reactivity :
Mouse, Bovine, Horse, Human, Monkey
Usage :
IHC, IHC-P (5 µg/ml), WB (0.2 - 1 µg/ml)
ShortWebDescription :
EGR2 antibody LS-B3577 is an unconjugated rabbit polyclonal antibody to EGR2 (aa397-446) from human. It is reactive with human, mouse, bovine and other species. Validated for IHC and WB. Cited in 2 publications.
UsageText :
Immunohistochemistry: LS-B3577 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3577 was determined to be 5 ug/ml.
Synonyms :
EGR2, CMT1D, CMT4E, Early growth response 2, E3 SUMO-protein ligase EGR2, EGR-2, KROX20, Krox-20, AT591, Zinc finger protein Krox-20
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.