This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ NPC / NPC1 Antibody (clone 17B5) LS-B3437
catalog :
LS-B3437
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
17B5

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
AntibodyID :
106109
AntibodyName :
LS-B3437
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ NPC / NPC1 Antibody (clone 17B5) LS-B3437
Specificity :
Reacts with the human NPC1 protein. Species cross-reactivity: Confirmed with an NPC1 transfected I1061T cell line.
ClonalityDesc :
Monoclonal
CloneName :
17B5
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.09% Sodium Azide
ImmunogenType :
Protein
ImmunogenDesc :
Fragments of Human NPC1 conjugated to a carrier protein.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
NPC / NPC1
StandardGeneSymbol :
NPC1
Reactivity :
Human
Usage :
IF (10 µg/ml), IHC, IHC-P (10 µg/ml), IP, WB (1 - 2 µg/ml)
ShortWebDescription :
NPC1 antibody LS-B3437 is an unconjugated mouse monoclonal antibody to human NPC1 (NPC). Validated for IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
UsageText :
Immunohistochemistry: LS-B3437 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3437 was determined to be 10 ug/ml.
Synonyms :
NPC1, NPC, Niemann-Pick C1 protein, Niemann-Pick disease, type C1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.