IHC-plus™ NKX3-1 Antibody (N-Terminus, clone 3-9) LS-B3435 | LifeSpan Biosciences LS-B3435 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ NKX3-1 Antibody (N-Terminus, clone 3-9) LS-B3435

catalog :

LS-B3435

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3-9

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Locke J, Zafarana G, Ishkanian A, Milosevic M, Thoms J, Have C, et al. NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy. Clin Cancer Res. 2012;18:308-16 pubmed publisher

image

image 1 :

Anti-NKX3-1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

product information

AntibodyID :

106107

AntibodyName :

LS-B3435

TargetSpecies :

Human

Host Species :

Mouse

Product Name :

IHC-plus™ NKX3-1 Antibody (N-Terminus, clone 3-9) LS-B3435

Specificity :

Reacts with human Nkx3.1 protein, and does not cross-react with mouse. On Western blots, this antibody detects a band at ~34kD. Reactivity has been confirmed with human LN Cap-FGC prostate carcinoma cell lysates.

ClonalityDesc :

Monoclonal

CloneName :

3-9

AntibodyModification :

Unconjugated

AntigenModification :

N-Terminus

PresentationDesc :

PBS, pH 7.4, 0.09% Sodium Azide

ImmunogenType :

Fusion protein

ImmunogenDesc :

Fusion protein containing the N-Terminus domain of the human Nkx3.1

PurificationDesc :

Protein A purified

RecommendedStorageDesc :

Short term: store at 4°C. Long term: store at -20°C.

IsotypeName :

IgG1

Gene :

NKX3-1

StandardGeneSymbol :

NKX3-1

Reactivity :

Human

Usage :

ELISA (0.1 - 1 µg/ml), IHC, IHC-Fr, IHC-P (10 µg/ml), WB (1 - 3 µg/ml)

ShortWebDescription :

NKX3-1 antibody LS-B3435 is an unconjugated mouse monoclonal antibody to human NKX3-1 (N-Terminus). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.

UsageText :

Immunohistochemistry: LS-B3435 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3435 was determined to be 10 ug/ml.

Synonyms :

NKX3-1, BAPX2, NK homeobox, family 3, A, NK3 homeobox 1, NKX3, NKX3.1, Homeobox protein Nkx-3.1, NKX3A

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.