This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2) LS-B3294
catalog :
LS-B3294
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
104555
AntibodyName :
LS-B3294
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2) LS-B3294
Specificity :
Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
ClonalityDesc :
Monoclonal
CloneName :
056B-214.2.4.2
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
BBS, 0.1% Sodium Azide
ImmunogenType :
Native protein
ImmunogenDesc :
Purified human C6
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
Complement C6
StandardGeneSymbol :
C6
Reactivity :
Human
Usage :
ELISA, Flo, IHC, IHC-P (10 µg/ml)
ShortWebDescription :
Complement C6 antibody LS-B3294 is an unconjugated mouse monoclonal antibody to human Complement C6 (C-Terminus). Validated for ELISA, Flow and IHC. Tested on 20 paraffin-embedded human tissues.
UsageText :
Immunohistochemistry: LS-B3294 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3294 was determined to be 10 ug/ml. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients.
Synonyms :
C6, Complement component C6, Complement C6, Complement component 6
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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