product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ UMOD / Uromodulin Antibody (clone 10.32, FITC) LS-B3105
catalog :
LS-B3105
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
10.32
reactivity :
human
application :
ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
LifeSpan Biosciences product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Turco A, Lam W, Rule A, Denic A, Lieske J, Miller V, et al. Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys. J Extracell Vesicles. 2016;5:29642 pubmed publisher
  • flow cytometry; human
Jayachandran M, Lugo G, Heiling H, Miller V, Rule A, Lieske J. Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. Biol Sex Differ. 2015;6:2 pubmed publisher
Chirackal R, Jayachandran M, Wang X, Edeh S, Haskic Z, Perinpam M, et al. Urinary extracellular vesicle-associated MCP-1 and NGAL derived from specific nephron segments differ between calcium oxalate stone formers and controls. Am J Physiol Renal Physiol. 2019;317:F1475-F1482 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B3105 image 1
Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.
product information
AntibodyID :
97915
AntibodyName :
LS-B3105
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IHC-plus™ UMOD / Uromodulin Antibody (clone 10.32, FITC) LS-B3105
Specificity :
Anti-human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. Tamm-Horsfall protein is a glycoprotein of approximately 80 kD containing up to 25% carbohydrate by weight.
ClonalityDesc :
Monoclonal
CloneName :
10.32
AntibodyModification :
FITC
PresentationDesc :
PBS, 0.02% Sodium Azide, BSA
ImmunogenType :
Purified protein
ImmunogenDesc :
Human Tamm-Horsfall protein
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
IsotypeName :
IgG2b
Gene :
UMOD / Uromodulin
StandardGeneSymbol :
UMOD
Reactivity :
Dog, Human
Usage :
ELISA, IF, IHC, IHC-Fr, IHC-P (1:50)
ShortWebDescription :
Uromodulin antibody LS-B3105 is an FITC-conjugated mouse monoclonal antibody to Uromodulin (UMOD) from human. It is reactive with human and dog. Validated for ELISA, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
UsageText :
Immunohistochemistry: LS-B3105 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3105 was determined to be 1:50. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
UMOD, ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, Uromucoid, Tamm-Horsfall glycoprotein, HNFJ1, Uromodulin
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.