product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IHC-plus™ PTCH2 / Patched 2 Antibody (aa226-235) LS-B301
catalog :
LS-B301
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, et al. Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human. Cell Rep. 2019;29:4553-4567.e7 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-B301 image 1
Anti-PTCH2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
product information
AntibodyID :
31260
AntibodyName :
LS-B301
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
IHC-plus™ PTCH2 / Patched 2 Antibody (aa226-235) LS-B301
Specificity :
Reacts with residues 226-235 [GPFASLEGFR] of the human PTCH2 protein. Cross reacts with mouse.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa226-235
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenDesc :
Residues 226-235 [GPFASLEGFR] of the human PTCH2 protein
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Gene :
PTCH2 / Patched 2
StandardGeneSymbol :
PTCH2
Reactivity :
Mouse, Human
Usage :
IHC, IHC-P (2.5 µg/ml)
ShortWebDescription :
Patched 2 antibody LS-B301 is an unconjugated rabbit polyclonal antibody to Patched 2 (PTCH2) (aa226-235) from human. It is reactive with human and mouse. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
UsageText :
Immunohistochemistry: LS-B301 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B301 was determined to be 2.5 ug/ml.
Synonyms :
PTCH2, Patched (Drosophila) homolog 2, Patched 2, Patched homolog 2, Patched homolog 2 (Drosophila), Protein patched homolog 2, PTC2
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.