IHC-plus™ IL1R1 Antibody (Extracellular Domain, clone L1-31-22.2.1) LS-B2859 | LifeSpan Biosciences LS-B2859 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ IL1R1 Antibody (Extracellular Domain, clone L1-31-22.2.1) LS-B2859

catalog :

LS-B2859

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

L1-31-22.2.1

reactivity :

human

application :

ELISA, immunohistochemistry, radioimmunoassay, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Prutsch N, Fock V, Haslinger P, Haider S, Fiala C, Pollheimer J, et al. The role of interleukin-1? in human trophoblast motility. Placenta. 2012;33:696-703 pubmed publisher

image

image 1 :

Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

product information

AntibodyID :

96533

AntibodyName :

LS-B2859

TargetSpecies :

Human

Host Species :

Mouse

Product Name :

IHC-plus™ IL1R1 Antibody (Extracellular Domain, clone L1-31-22.2.1) LS-B2859

Specificity :

These antibodies react with cell surface and soluble human IL-1 receptor; Specific epitopes are unknown, but they do partially inhibit (30-50%) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.

ClonalityDesc :

Monoclonal

CloneName :

L1-31-22.2.1

AntibodyModification :

Unconjugated

AntigenModification :

Extracellular Domain

PresentationDesc :

PBS, pH 7.4

ImmunogenType :

Protein

ImmunogenDesc :

The extracellular domain of the type I human IL-1 receptor.

PurificationDesc :

Protein G purified

RecommendedStorageDesc :

Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.

IsotypeName :

IgG2b

Gene :

IL1R1

StandardGeneSymbol :

IL1R1

gene family :

Interleukin

Reactivity :

Human

Usage :

ELISA, IHC, IHC-P (10 µg/ml), RIA

UsageNotRecommended :

ShortWebDescription :

IL1R1 antibody LS-B2859 is an unconjugated mouse monoclonal antibody to human IL1R1 (Extracellular Domain). Validated for ELISA, IHC and RIA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.

UsageText :

Immunohistochemistry: LS-B2859 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2859 was determined to be 10 ug/ml. ELISA: Can be used as capture reagents or second antibody at a concentration of 5 ug/ml. RIA: Concentrations of 20-30 ng/ml of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunocytochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 ug/ml.

Synonyms :

IL1R1, Antigen CD121a, D2S1473, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, IL1R, IL1RA, IL1RT1, Interleukin receptor 1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, CD121A, CD121a antigen, Interleukin 1 receptor, type I, Interleukin-1 receptor type I, Interleukin-1 type i receptor, p80

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.